Three-Component Synthesis of Tetrahydroisoquinolines Based on the SNVin Reaction

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详细

A three-component reaction of carbocyclic enaminoketones, CH-acids, and electrophiles was studied. Based on the reaction of nucleophilic vinyl substitution (SNVin), previously unknown derivatives of 5,6,7,8-tetrahydroisoquinolines were synthesized. The structure of a number of products was studied by X-ray diffraction.

作者简介

I. Dyachenko

Lugansk State Pedagogical University

ORCID iD: 0000-0001-7255-3446
Lugansk, Russia

V. Dyachenko

Lugansk State Pedagogical University

ORCID iD: 0000-0002-0993-4091
Lugansk, Russia

P. Dorovatovskii

National Research Center "Kurchatov Institute"

Moscow, Russia

V. Khrustal'ev

Peoples' Friendship University of Russia (RUDN University); Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

ORCID iD: 0000-0001-8806-2975
Moscow,Russia;Moscow, Russia

V. Nenajdenko

Lomonosov Moscow State University

Email: nenajdenko@gmail.com
ORCID iD: 0000-0001-9162-5169
Moscow, Russia

参考

  1. Yoshizumi T., Miyazo H., Sugimoto Y., Takahashi H., Okamoto O. Synthesis. 2005, 10, 1593–1600. doi: 10.1055/s-2005-865306
  2. Пароникян Е.Г., Норавян А.С., Акопян Ш.Ф., Джагацпанян И.А., Назарян И.М., Пароникян Р.Г Хим.-фарм. журн. 2007, 41, 14–16. doi: 10.1007/s11094-007-0102-6
  3. Пароникян Е.Г., Дашян Ш.Ш., Паносян Г.А., Айвазян А.Г., Тамазян Р.А. ХГС, 2018, 54, 804–811. doi: 10.1007/s10593-018-2353-4
  4. Бабаев Е.В., Коваль Я.И., Рыбаков В.Б., Пароникян Е.Г., Степанян Г.М., Пароникян Р.Г., Дашян Ш.Ш., Ржевский С.А., Шадрин И.А. Изв. АН Сер. хим. 2018, 67, 313–320. doi: 10.1007/s11172-018-2076-9
  5. Cavasotto C.N., Ortiz M.A., Abagyan R.A., Piedrafita F.J. Bioorg. Med. Chem. Lett. 2006, 16, 1969–1974. doi: 10.1016/j.bmcl.2005.12.067
  6. Ferlin M.G., Gia O., Dalla Via L. Chem. Med. Chem. 2011, 6, 1872–1883. doi: 10.1002/cmdc.201100233
  7. Ashwell G.J., Whittam A.J., Amiri M.A., Hamilton R. J. Mater. Chem. 2001, 11, 1345–1350. doi: 10.1039/b009911m
  8. Ashwell G.J., Robinson B.J., Amiri M.A., Locatelli D., Quici S., Roberto D. J. Mater. Chem. 2005, 15, 4203–4205. doi: 10.1039/b506765k
  9. Ashwell G.J., Tyrrell W.D., Whittam A.J. JACS. 2004, 126, 7102–7110. doi: 10.1021/ja049633u
  10. Reichelf C., Schulze A. Daghish M., Leistner S. Заявка 1623987 (2006). EIIB. PЖХим. 2007. 07.10–19O.115П.
  11. Дяченко В.Д., Сукач С.М., Морковник А.С. ЖОрХ. 2020, 56, 829–858 [Dyachenko V.D., Sukach S.M. Morkovnik A.S. Russ. J. Org. Chem. 2020, 56, 949–973.] doi: 10.1134/S1070428020060019
  12. Дяченко И.В., Дяченко В.Д. ЖОрХ. 2017, 53, 1735–1754. [Dyachenko I.V., Dyachenko V.D. Russ. J. Org. Chem. 2017, 53, 1769–1787.] doi: 10.1134/S1070428017120016
  13. Дяченко И.В., Дяченко В.Д., Дороватовский П.В., Хрусталев В.Н., Ненайденко В.Г. ЖОрХ. 2022, 58, 469–475. doi: 10.1134/S1070428022050025
  14. Ненайденко В.Г. Усп. хим. 2020, 89, 1274–1336. doi: 10.1070/RCR5010
  15. Шаинян Б.А. Изв. Сиб. отд. АН СССР. 1990, 4, 137–144.
  16. Rappoport Z. Acc. Chem. Res. 1992, 25, 474–479. doi: 10.1021/ar00022a007
  17. Bruker, SAINT, Bruker AXS Inc., Madison, WI, 2013.
  18. Krause L., Herbst-Irmer R., Sheldrick G.M. Stalke D., J. Appl. Cryst. 2015, 48, 3–10. doi: 10.1107/S1600576714022985
  19. Sheldrick G.M. Acta Cryst. 2015, C71, 3–8. doi: 10.1107/S2053229614024218

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