A New-fangled COVID-19 Variant, Eris, Might be the One to Lookout in 2023 or far from Over
- Authors: Ray S.1, Mukherjee S.2
-
Affiliations:
- ,
- Department of Biochemistry, All India Institute of Medical Science
- Issue: Vol 24, No 6 (2024)
- Section: Medicine
- URL: https://vietnamjournal.ru/1871-5265/article/view/645670
- DOI: https://doi.org/10.2174/0118715265276833240105110046
- ID: 645670
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Abstract
Coronavirus Disease-19 (COVID-19) is an infectious disease brought on by the extremely pathogenic and contagious severe acute respiratory syndrome-virus-2 (SARS-CoV-2). The agenda for the COVID-19 pandemic is dynamic and includes recent developments. Seven variants under monitoring (VUMs), one variant of interest (VOI), XBB.1.5, and their offspring lineages are currently being actively monitored by WHO. The VUMs are BA.2.75, CH.1.1, BQ.1, XBB (with the exception of XBB.1.5, XBB.1.16, and XBB.1.9.1), XBF, and XBB.1.16. With 95 countries having reported finding XBB.1.5 (VOI), it is still the most common strain worldwide, responsible for 47.9% of cases from epidemiological January to March 2023. Seventy nations discovered XBB.1.5 in February and March 2023 and posted sequencing data to GISAID. Of the 43 nations that uploaded more than 50 sequences, XBB.1.5 prevalence has increased to more than 50% in 11 nations. Over 23000 deaths and 3 million new cases were recorded globally in March and April 2023. Worldwide detection of a new COVID-19 strain has prompted specialists to issue a warning that the virus is \"circulating unchecked\". The Greek goddess of conflict and discord Eris has inspired the nicknaming of EG 5.1, a subvariant of Omicron. The strain is becoming more prevalent in the USA and cases are increasing in the UK. The severity of each SARS-CoV2 variant has been comparable, although a more severe form might develop. Eris is an ancestor of Omicron and exhibits some of its characteristics. Reinfection risk can be influenced by a variety of variables, including age, location, and health equity and the COVID-19 vaccine is more or less effective depending on the strain.
About the authors
Suman Ray
,
Email: info@benthamscience.net
Sukhes Mukherjee
Department of Biochemistry, All India Institute of Medical Science
Author for correspondence.
Email: info@benthamscience.net
References
- Kang S, Peng W, Zhu Y, et al. Recent progress in understanding 2019 novel coronavirus (SARS-CoV-2) associated with human respiratory disease: Detection, mechanisms and treatment. Int J Antimicrob Agents 2020; 55(5): 105950. doi: 10.1016/j.ijantimicag.2020.105950 PMID: 32234465
- Ray SK, Mukherjee S. Understanding the role of corona virus based on current scientific evidence - A review with emerging importance in pandemic. Recent Patents Anti-Infect Drug Disc 2020; 15(2): 89-103. doi: 10.2174/1574891X15999200918144833 PMID: 32957894
- Shereen MA, Khan S, Kazmi A, Bashir N, Siddique R. COVID-19 infection: Emergence, transmission, and characteristics of human coronaviruses. J Adv Res 2020; 24: 91-8. doi: 10.1016/j.jare.2020.03.005 PMID: 32257431
- Ather A, Patel B, Ruparel NB, Diogenes A, Hargreaves KM. Coronavirus disease 19 (COVID-19): Implications for clinical dental care. J Endod 2020; 46(5): 584-95. doi: 10.1016/j.joen.2020.03.008 PMID: 32273156
- Gorbalenya AE, Baker SC, Baric RS, et al. The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2. Nat Microbiol 2020; 5(4): 536-44. doi: 10.1038/s41564-020-0695-z PMID: 32123347
- Polatoğlu I, Oncu-Oner T, Dalman I, Ozdogan S. COVID-19 in early 2023: Structure, replication mechanism, variants of SARS-CoV-2, diagnostic tests, and vaccine & drug development studies. MedComm 2020; 4(2): e228.
- Mohapatra RK, Tiwari R, Sarangi AK, et al. Twin combination of omicron and delta variants triggering a tsunami wave of ever high surges in COVID-19 cases: A challenging global threat with a special focus on the Indian subcontinent. J Med Virol 2022; 94(5): 1761-5. doi: 10.1002/jmv.27585 PMID: 35014038
- Available from: https://www.outlookindia.com/website/story/business-news-what-is-florona-not-a/408079(Last accessed on August 26, 2023).
- The COVID-19 pandemic in 2023: Far from over. Lancet 2023; 401(10371): 79. doi: 10.1016/S0140-6736(23)00050-8 PMID: 36641201
- Available from: https://economictimes.indiatimes.com/news/international/uk/health-experts-issue-warning-as-eris-variant-rapidly-spreads-across-uk-one-in-seven-COVID-cases-attributed-to-new-variant/articleshow/102430337.cms?utm_source=contentofinterest&utm_medium=text&utm_campaign=cppst (Last accessed on August 26, 2023)
- Available from: https://www.cbsnews.com/news/COVID-variant-eg-5-now-eris/ (Last accessed on August 26, 2023)
- Available from: https://www.hindustantimes.com/lifestyle/health/new-COVID-variant-eris-spreading-rapidly-in-uk-know-symptoms-and-prevention-measures-101691407657712.html(Last accessed on August 26, 2023).
- Mukherjee S, Ray SK. A new wave of COVID-19 in 2021 with unique genetic characters - Present global scenario and beholding onwards. Infect Disord Drug Targets 2022; 22(6): e010422202932. doi: 10.2174/1871526522666220401101818 PMID: 35366784
- Available from: https://www.hindustantimes.com/lifestyle/health/new-COVID-variant-eris-spreading-rapidly-in-uk-know-symptoms-and-prevention-measures-101691407657712.html(Last accessed on August 26, 2023)
- Looi MK. Covid-19: Hospital admissions rise in England amid fears of new variant and waning immunity. BMJ 2023; 382: p1833. doi: 10.1136/bmj.p1833 PMID: 37553176
- Available from: https://covid.cdc.gov/covid-data-tracker/#variants-genomic-surveillance (Last accessed on August 26, 2023)
- Looi MK. How are COVID-19 symptoms changing. BMJ 2023; 380(3) doi: 10.1136/bmj.p3
- Mahase E. COVID-19: WHAT DO WE KNOW ABOUT XBB.1.5 AND SHOULD WE BE WORRIED? BMJ 2023; 380: 153. doi: 10.1136/bmj.p153
- Available from: https://erictopol.substack.com/p/the-virus-is-learning-new-tricks (Last accessed on August 26, 2023)
- Available from: https://www.ecdc.europa.eu/en/news-events/ecdc-classifies-xbb15-lineages-amino-acid-change-f456l-variants-interest-following (Last accessed on August 26, 2023)
- Available from: https://www.nebraskamed.com/COVID/what-COVID-19-variants-are-going-around (Last accessed on August 26, 2023)
- Available from: https://www.nebraskamed.com/COVID/what-COVID-19-variants-are-going-around (Last accessed on August 26, 2023)
- Available from: https://www.india.com/health/new-COVID-variant-eris-how-is-it-different-from-other-strains-and-who-is-more-at-risk-of-contracting-it-6213093/ (Last accessed on August 26, 2023)
- Available from: https://www.hindustantimes.com/lifestyle/health/new-COVID-variant-eris-spreading-rapidly-in-uk-know-symptoms-and-prevention-measures-101691407657712.html (Last accessed on August 26, 2023)
- Available from: https://www.cnbc.com/2023/08/18/covid-new-vaccines-will-likely-protect-against-eris-variant.html (Last accessed on August 26, 2023)
- Available from: https://www.reuters.com/business/healthcare-pharmaceuticals/new-covid-vaccines-are-way-eris-variant-rises-2023-08-14/ (Last accessed on August 26, 2023)
- Available from: https://www.reuters.com/business/healthcare-pharmaceuticals/modernas-updated-covid-vaccine-effective-against-eris-variant-humans-2023-08-17/ (Last accessed on August 26, 2023)
- Mukherjee S, Ray SK. Challenges in engendering herd immunity to SARS-CoV-2 infection: Possibly impossible but plausibile. Infect Disord Drug Targets 2022; 22(4): e170122200309. doi: 10.2174/1871526522666220117153838 PMID: 35040409
- Rubio-Casillas A, Redwan EM, Uversky VN. SARS-CoV-2: A master of immune evasion. Biomedicines 2022; 10(6): 1339. doi: 10.3390/biomedicines10061339 PMID: 35740361
- Ali I, Alharbi OML. COVID-19: Disease, management, treatment, and social impact. Sci Total Environ 2020; 728: 138861. doi: 10.1016/j.scitotenv.2020.138861 PMID: 32344226
- Jeyanathan M, Afkhami S, Smaill F, Miller MS, Lichty BD, Xing Z. Immunological considerations for COVID-19 vaccine strategies. Nat Rev Immunol 2020; 20(10): 615-32. doi: 10.1038/s41577-020-00434-6 PMID: 32887954
- Ray SK, Mukherjee S. From bench side to bed-travelling on a road to get a safe and effective vaccine against covid-19, day to save the life. Recent Pat Biotechnol 2022; 16(1): 2-5. doi: 10.2174/1872208315666211209094457 PMID: 34886784
- Martinelli L, Kopila V, Vidmar M, et al. Face masks during the COVID-19 Pandemic: A simple protection tool with many meanings. Front Public Health 2021; 8: 606635. doi: 10.3389/fpubh.2020.606635 PMID: 33520918
- Available from: https://www.who.int/emergencies/diseases/novel-coronavirus-2019/advice-for-public (Last accessed on August 26, 2023)
- Available from: https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/prevention.html (Last accessed on August 26, 2023)
- Available from: https://www.nidirect.gov.uk/articles/coronavirus-covid-19-how-stay-safe-and-help-prevent-spread (Last accessed on August 26, 2023)
- Zella D, Giovanetti M, Cella E, et al. The importance of genomic analysis in cracking the coronavirus pandemic. Expert Rev Mol Diagn 2021; 21(6): 547-62. doi: 10.1080/14737159.2021.1917998 PMID: 33849359
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