Anxious and melancholic depression are followed by differently directed serum albumin conformation
- 作者: Uzbekov M.G.1, Smolina N.V.1, Syrejshchikova T.I.1, Maximova N.M.1, Shikhov S.N.1, Dobretsov G.E.1, Brilliantova V.V.1, Krjukov V.V.1
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隶属关系:
- Moscow Research Institute of Psychiatry
- 期: 卷 41, 编号 1 (2024)
- 页面: 14-18
- 栏目: Clinical Neurochemistry
- URL: https://vietnamjournal.ru/1027-8133/article/view/653910
- DOI: https://doi.org/10.31857/S1027813324010022
- EDN: https://elibrary.ru/GZHVIJ
- ID: 653910
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详细
The aim of the study was investigation of the peculiarities of the conformational changes of serum albumin in patients with anxious and melancholic depression. Albumin conformation was measured by the method of the subnanosecond laser time resolved fluorescence spectroscopy. Anxious depression was followed with the significant decrease of the values of the three amplitudes on the serum albumin in comparison with controls. In the melancholic depression the values of all three amplitudes on serum albumin molecules were significantly elevated in comparison with controls. These results are clearly indicated that anxious and melancholic depression are followed by differently directed changes in serum albumin conformation.
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作者简介
M. Uzbekov
Moscow Research Institute of Psychiatry
编辑信件的主要联系方式.
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
N. Smolina
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
T. Syrejshchikova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
N. Maximova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
S. Shikhov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
G. Dobretsov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
V. Brilliantova
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
V. Krjukov
Moscow Research Institute of Psychiatry
Email: uzbekovmg@gmail.com
俄罗斯联邦, Moscow
参考
- Goodvin F.K., Jamison K.R. Maniac Depressive Illness: Bipolar Disorders and Recurrent Depression. N.Y.: Oxford University Press, 2007. 159 p.
- World Health Assembly. Global Burden of Mental Disorders and the Need for a Comprehensive, Coordinated Response from Health and Social Sectors at the Country Level // Report by the Secretariat World Health Organization, Geneva, Switzerland. 2012.
- Spinney L. // Eur. Psychiatry. 2009. V. 24. P. 550–551.
- Краснов В.Н. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2012. Т. 112. Вып. 2. Депрессия. С. 3–11.
- Сахаров В.Н., Литвицкий П.Ф. // Вестник РАМН. 2016. Т. 71. № 1. С. 46–51.
- Dobretsov G.E., Syrejshchikova T.I., Smolina N.V., and Uzbekov M.G. // Human Serum Albumin, Ed. Stokes T.N.Y: Nova Science Publishers. 2015. P. 129–171.
- Hamilton M. Handbook of Anxiety Disorders / Eds. Last C., Hersen M. Oxford: Pergamon Press. 1988. P. 143–155.
- Сырейщикова Т.И., Смолина Н.В., Узбеков М.Г., Добрецов Г.Е., Калинина В.В., Крюков В.В., Антипова О.С., Емельянова И.Н., Краснов В.Н. // Журнал неврологии и психиатрии имени С.С. Корсакова. 2015. Т. 115. № 1. Вып. 2. С. 56–59.
- Uzbekov M., Misionzhnik E., Maximova N., Vertogradova O. // Human Psychopharmacology: Clinical and Experimental. 2006. V. 21. P. 109–115.
- Gryzunov Yu.A., Dobretsov G.E. Protein Conformation: New Research / Ed. Roswell L.B. N. Y.: Nova Publ., 2008. P. 125–159.
- Узбеков М.Г., Смолина Н.В., Сырейщикова Т.И., Бриллиантова В.В., Добрецов Г.Е., Шихов С.Н. // Нейрохимия. 2022. Т. 39. № 4. С. 78–84.
- Узбеков М.Г. // Социальная и клиническая психиатрия. 2022. Т. 32. № 3. С. 83–87.
- Бриллиантова В.В., Смолина Н.В., Сырейщикова Т.И., Узбеков М.Г., Добрецов Г.Е. // Нейрохимия. 2018. Т. 35. № 1. С. 96–100.
- Узбеков М.Г. // Биохимия. 2023, Т. 88. Вып. 4. С. 600–613.
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