Neurodevelopmental Disorders in Children: Neuroplasticity and Possibilities of Nootropic Pharmacotherapy
- Authors: Zavadenko N.N.1
-
Affiliations:
- Pirogov Russian National Research Medical University
- Issue: Vol 40, No 2 (2023)
- Pages: 146-156
- Section: Review Articles
- URL: https://vietnamjournal.ru/1027-8133/article/view/653945
- DOI: https://doi.org/10.31857/S102781332302022X
- EDN: https://elibrary.ru/UDKOBD
- ID: 653945
Cite item
Abstract
Neurodevelopmental Disorders (NDD) are characterized by disturbances of the formation of cognitive functions, communication skills, behavior characteristics and / or motor skills, which are caused by abnormalities in the course of the processes of neuroontogenesis. Factors of the etiology and pathogenesis of NDD include genetic mechanisms, early damage to the developing brain, and adverse external influences. Most forms of NDD manifest themselves in the early stages of development and before the child begins school eduction. The most common NDD, with which medical doctors of various specialties constantly meet, include speech development disorders and attention deficit hyperactivity disorder (ADHD). Since disorders of neuroplasticity processes are considered among the mechanisms of the NDD pathogenesis, their therapy should be aimed at restoring and stimulating the neuroplasticity potential. Manifestations of NDD, undergoing age-related evolution, significantly disrupt normal life and have an adverse effect on various functional areas not only in children, but also in adolescents and adults. The increase in symptoms in patients with NDD at one age or another is not due to the progressive nature of cerebral changes, but to increased difficulties of adaptation with increasing loads, including educational, social, professional ones. Therefore, in most cases, they require many years of complex management and the use of pharmacotherapy, the prospects of which are primarily associated with nootropic drugs. The data of new studies on the effectiveness of nootropics in developmental dysphasia and ADHD are discussed, and possible mechanisms of the nootropics influence on neuroplasticity processes are considered.
About the authors
N. N. Zavadenko
Pirogov Russian National Research Medical University
Email: nchjournal@gmail.com
Russia, Moscow
References
- Boivin M.J., Kakooza A.M., Warf B.C., Davidson L.L., Grigorenko E.L. // Nature. 2015. V. 527 (7578). S. 155–160. https://doi.org/10.1038/nature16029
- World Health Organization. International statistical classification of diseases and related health problems (11th ed.). 2019. https://icd.who.int/.
- Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-V) / Arlington, VA: American Psychiatric Association, 2013. 947 p.
- Morris-Rosendahl D.J., Crocq M.A. // Dialogues Clin. Neurosci. 2020. V. 22(1). P. 65–72. https://doi.org/10.31887/DCNS.2020.22.1/macrocq
- Arnett A.B., Wang T., Eichler E.E., Bernier R.A. // J. Neurodevelopmental Disorders. 2021. V. 13(1). № 24. https://doi.org/10.1186/s11689-021-09371-4
- Parenti I., Rabaneda L.G., Schoen H., Novarino G. // Trends in Neurosciences. 2020. V. 43(8). P. 608–621. https://doi.org/10.1016/j.tins.2020.05.004
- Smith M.R., Glicksberg B.S., Li L., Chen R., Morishita H., Dudley J.T. // Pac. Symp. Biocomput. 2018. V. 23. P. 68–79.
- Neville H., Bavelier D. // Prog. Brain Res. 2002. V. 138. P. 177–188. https://doi.org/10.1016/S0079-6123(02)38078-6
- Meredith R.M. // Neurosci. Biobehav. Rev. 2015. V. 50. P. 180–188. https://doi.org/10.1016/j.neubiorev.2014.12.001
- Rapoport J.L., Gogtay N. // Neuropsychopharmacology. 2008. V. 33(1). P. 181–197. https://doi.org/10.1038/sj.npp.1301553
- Заваденко Н.Н., Холин А.А., Заваденко А.Н., Мичурина Е.С. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2018. Т. 118. № 8. С. 118–125. https://doi.org/10.17116/jnevro2018118081118
- Collisson B.A., Graham S.A., Preston J.L., Sarah Rose M., McDonald S., Tough S. // J. Pediatr. 2016. V. 172. P. 168–174. e1. https://doi.org/10.1016/j.jpeds.2016.02.020
- Vogel J.P., Chawanpaiboon S., Moller A.B., Watananirun K., Bonet M., Lumbiganon P. // Best Pract. Res. Clin. Obstet. Gynaecol. 2018. V. 52. P. 3–12. https://doi.org/10.1016/j.bpobgyn.2018.04.003
- Sansavini A., Guarini A., Justice L.M., Savini S., Broccoli S., Alessandroni R., Faldella G. Early Human Dev. 2010. V. 86. № 12. P. 765–772. https://doi.org/10.1016/j.earlhumdev.2010.08.014
- Barre N., Morgan A., Doyle L.W., Anderson P.J. // The Journal of Pediatrics. 2011. V. 158. № 5. P. 766–774. e1. https://doi.org/10.1016/j.jpeds.2010.10.032
- Ismail F.Y., Fatemi A., Johnston M.V. // Eur. J. Paediatr. Neurol. 2017. V. 21. № 1. P. 23–48. https://doi.org/10.1016/j.ejpn.2016.07.007
- Боголепова А.Н., Чуканова Е.И. // Журн. неврологии и психиатрии им. C.C. Корсакова. 2010. Т. 110. № 8. С. 62–65.
- Tsai S.J. // Cytokine Growth Factor Rev. 2017. V. 34. P. 35–41. https://doi.org/10.1016/j.cytogfr.2016.11.003
- Bilgiç A., Ferahkaya H., Kilinç İ., Energin V.M. // Noro Psikiyatr Ars. 2021. V. 58. № 2. P. 128–132. https://doi.org/10.29399/npa.27274
- Kurkin D.V., Bakulin D.A., Morkovin E.I., Kalatanova A.V., Makarenko I.E., Dorotenko A.R., Kovalev N.S., Dubrovina M.A., Verkholyak D.V., Abrosimova E.E., Smir-nov A.V., Shmidt M.V., Tyurenkov I.N. PLoS One. 2021. V. 16. № 7. e0254493. https://doi.org/10.1371/journal.pone.0254493
- Law J., Dennis J.A., Charlton J.J.V. // Cochrane Database of Systematic Reviews. 2017. Issue 1. Art. № CD012490.
- Заваденко Н.Н., Давыдова Л.А., Суворинова Н.Ю. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2020. Т. 120. № 10. С. 38–44. https://doi.org/10.17116/jnevro202012010138
- Гомазков О.А. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2015. Т. 115. № 8. С. 99–104. https://doi.org/10.17116/jnevro20151158199-104
- Гуляева Н.В. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2018. Т. 118. № 10. С. 93–96. https://doi.org/10.17116/jnevro201811810193
- Яковлев А.А., Гуляева Н.В. // Нейрохимия. 2017. Т. 34. № 1. С. 91–96. https://doi.org/10.7868/S1027813316040166
- Демченко А.В., Беленичев И.Ф. // Нейрохимия. 2016. Т. 10. № 1. С. 64–68. https://doi.org/10.7868/S1027813316010052
- Чутко Л.С., Сурушкина С.Ю. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2020. Т. 120. № 2. С. 120–124. https://doi.org/10.17116/jnevro2020120021120
- Заваденко Н.Н. // Гиперактивность и дефицит внимания в детском возрасте. 2-е изд., перераб. и доп. М.: Юрайт, 2019, 274 с.
- Wolraich M.L., Hagan J.F., Allan C., Chan E., Davison D., Earls M., Evans S.W., Flinn S.K., Froehlich T., Frost J., Holbrook J.R., Lehmann C.U., Lessin H.R., Okechukwu K., Pierce K.L., Winner J.D., Zurhellen W. // Pediatrics. 2019. V. 144. № 4. e20192528. https://doi.org/10.1542/peds.2019-2528
- Banaschewski T., Becker K., Döpfner M., Holtmann M., Rösler M., Romanos M. // Dtsch. Ärztebl. Int. 2017. V. 114. P. 149–159. https://doi.org/10.3238/arztebl.2017.0149
- Demontis D., Walters R.K., Martin J. et al. // Nat. Genet. 2019. V. 51. P. 63–75. https://doi.org/10.1038/s41588-018-0269-7
- Joseph N., Zhang-James Y., Perl A., Faraone S.V. // J. Atten. Disord. 2015. V. 19. № 11. P. 915–924. https://doi.org/10.1177/1087054713510354
- Nasim S., Naeini A.A., Najafi M., Ghazvini M., Hassanzadeh A. // Int J Prev Med. 2019. V. 10. P. 41. https://doi.org/10.4103/ijpvm.IJPVM_80_18
- Corona J.C. // Antioxidants (Basel). 2020. V. 9. № 11. 1039. https://doi.org/10.3390/antiox9111039
- Alvarez-Arellano L., González-García N., Salazar-García M., Corona J.C. // Antioxidants (Basel). 2020. V. 9. № 2. 176. https://doi.org/10.3390/antiox9020176
- Curpan A.S., Luca A.C., Ciobica A. // Oxid. Med. Cell. Longev. 2021. P. 6640206. https://doi.org/10.1155/2021/6640206
- Щулькин А.В. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2018. Т. 118. № 12. Вып. 2. С. 87–93. https://doi.org/10.17116/jnevro201811812287
- Заваденко Н.Н., Суворинова Н.Ю., Батышева Т.Т., Быкова О.В., Платонова А.Н., Гайнетдинова Д.Д., Левитина Е.В., Машин В.В., Вакула И.Н., Максимова Н.Е. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2022. Т. 22. № 4. С. 75–86. https://doi.org/10.17116/jnevro202212204175
- Заваденко Н.Н., Суворинова Н.Ю., Вакула И.Н., Малинина Е.В., Кузенкова Л.М. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2017. Т. 117. № 5. С. 39–45. https://doi.org/10.17116/jnevro20171175139-45
- Ковалёв Г.И., Сухорукова Н.А., Васильева Е.В., Кондрахин Е.А., Салимов Р.М. // Биомедицинская химия. 2021. Т. 67. Вып. 5. С. 402–410. https://doi.org/10.18097/PBMC20216705402
- Заваденко Н.Н., Макушкин Е.В., Гайнетдинова Д.Д., Колоколов О.В., Малинина Е.В., Антипенко Е.А., Сагутдинова Э.Ш., Халецкая О.В., Дмитриев А.В., Маслова Н.Н., Машин В.В., Пантелеева М.В. // Журнал неврологии и психиатрии им. С.С. Корсакова. 2022. Т. 22. № 11. С. 62–68. https://doi.org/10.17116/jnevro202212211162
- Tarasov S.A., Gorbunov E.A., Don E.S., Emelyanova A.G., Kovalchuk A.L., Yanamala N., Schleker A.S.S., Klein-Seetharaman J., Groenestein R., Tafani J.P., van der Meide P., Epstein O.I. // The Journal of Immunology. 2020. V. 205. № 5. P. 1345–1354. https://doi.org/10.4049/jimmunol.2000098
- Woods K.N. // Scientific Reports. 2021. V. 1. № 1. P. 13774. https://doi.org/10.1038/s41598-021-93326-1
- Khacheva K.K., Khakimova G.R., Glazunov A.B., Fateeva V.V. / In Kalinin V.V., Hocaoglu C., Mohamed S. (Eds.), Anxiety Disorders – The New Achievements // IntechOpen. 2021. https://doi.org/10.5772/intechopen.92207
- Keller T.A., Just M.A. // Neuroimage. 2016. V. 125. P. 256–266. https://doi.org/10.1016/j.neuroimage.2015.10.015
- Vértes P., Bullmore E. // Journal of Child Psychology & Psychiatry. 2015. V. 56. № 3. P. 299–320. https://doi.org/10.1111/jcpp.12365
Supplementary files
