TOXICITY OF DIOCTYLTEREPHTHALATE

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Dioctylterephthalate is a general-purpose plasticizer, has low toxicity, and does not irritate the mucous membranes of the eye and the skin; the maximum nonlethal dose (DL0) for dioctylterephthalate after intragastric administration is set at 10,000 mg/kg. Indicative safe exposure level for dioctylterephthalate in ambient air in urban and rural settlements is recommended at 0.5 mg/m3. Substance has low acute toxicity; the maximum inactive dose is set at 4 mg/kg. The substance has low solubility in water (0.4 μg/l), does not affect the dynamics of biochemical oxygen consumption. Threshold concentration in water on organoleptic characteristic is set at 0.25 mg/l as for low hazard substances.

Sobre autores

R. Mamonov

Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.

Autor responsável pela correspondência
Email: fake@neicon.ru
119121, Moscow. Rússia

L. Fedotova

Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health; Russian Medical Academy of Continuous Professional Education, RF Ministry of Health.

Email: fake@neicon.ru

119121, Moscow.

125993, Moscow.

Rússia

I. Pechnikova

Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.

Email: fake@neicon.ru
119121, Moscow. Rússia

T. Potapchenko

Center for Strategic Planning and Management of Biomedical Health Risks, RF Ministry of Health.

Email: fake@neicon.ru
119121, Moscow. Rússia

Bibliografia

  1. Temporary methodical instructions on justification of maximum permissible concentrations (MPC) of pollutants in atmospheric air of inhabited places, VMU No. 4681-88. (n Russian)
  2. Justification of hygienic standards of chemicals in water of water objects of economicdrinking and cultural-household water use: Methodical instructions. MU 2.1.5.720-8. - M.: Federal center of Gossanepidnadzor of the Ministry of Health of the Russian Federation, 1999. (n Russian)

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Declaração de direitos autorais © Mamonov R.A., Fedotova L.A., Pechnikova I.A., Potapchenko T.D., 2018


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