Pectins in prevention of acute poisoning
- Autores: Ivnitsky Y.Y.1, Krasnov K.A.1, Rejniuk V.L.1, Lapina N.V.1, Melikhova M.V.1, Golovko A.I.1, Krasnova A.A.1
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Afiliações:
- Institute of Toxicology of the Federal Medical Biological Agency
- Edição: Nº 2 (2020)
- Páginas: 30-35
- Seção: Articles
- ##submission.datePublished##: 15.05.2020
- URL: https://vietnamjournal.ru/0869-7922/article/view/641206
- DOI: https://doi.org/10.36946/0869-7922-2020-2-29-34
- ID: 641206
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Resumo
The purpose of the review is to analyze the possibilities of using of pectin enterosorbents for the prevention of acute poisoning. Low-esterified pectins exhibit high sorbing activity against multicharged cations, are highly adhesive to the mucous membranes of the digestive tract and are able to reduce non-specifically the permeability of the enterohematic barrier. The expected duration of the preventive effect of pectin enterosorbents is 4-5 hours after their administration. In combination with good tolerability and ease of use, this indicates the prospects of low-esterified pectins as means of drug prevention of acute poisoning in case of increased risk of oral or inhalation intake of heavy metals, nuclear fission materials and nuclear fission products.
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Sobre autores
Yu. Ivnitsky
Institute of Toxicology of the Federal Medical Biological Agency
Autor responsável pela correspondência
Email: neugierig@mail.ru
Ivnitsky Yury Yurievich
192019, Saint Petersburg
RússiaK. Krasnov
Institute of Toxicology of the Federal Medical Biological Agency
Email: krasnov_tox@mail.ru
Krasnov Konstantin Andrejevich
192019, Saint Petersburg
RússiaV. Rejniuk
Institute of Toxicology of the Federal Medical Biological Agency
Email: vladton@mail.ru
Rejniuk Vladimir Leonidovich
192019, Saint Petersburg
RússiaN. Lapina
Institute of Toxicology of the Federal Medical Biological Agency
Email: lapina2005@inbox.ru
Lapina Natalja Vadimovna
192019, Saint Petersburg
RússiaM. Melikhova
Institute of Toxicology of the Federal Medical Biological Agency
Email: melihovamarina@inbox.ru
Melikhova Marina Valentinovna
192019, Saint Petersburg
RússiaA. Golovko
Institute of Toxicology of the Federal Medical Biological Agency
Email: prgolovko@inbox.ru
Golovko Alexandr Ivanovich
192019, Saint Petersburg
RússiaA. Krasnova
Institute of Toxicology of the Federal Medical Biological Agency
Email: apreski@mail.ru
Krasnova Alexandra Andrejevna
192019, Saint Petersburg
RússiaBibliografia
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