ASSESSMENT OF TOXICITY OF GERMANIUM COORDINATION COMPOUNDS

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Abstract

The synthesis of biologically active coordination compounds and the design on their basis of effective pharmacological preparations is currently the promising area. This paper presents the results of the toxicological studies on digermanium and its complex derivatives. It should be noted that the positive medical properties of organometallic compounds of germanium are confirmed by numerous studies, therefore, the development of the methods of synthesis, as well as investigations of physicochemical and pharmacological properties of these compounds are at the center of attention.

About the authors

A. V. Kadomtsevа

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Author for correspondence.
Email: rector@pimunn.ru
Кадомцева Алёна Викторовна (Kadomtsevа Alena Viktorovna), кандидат химических наук, старший преподаватель кафедры общей химии Russian Federation

I. V. Zhdanovich

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Email: rector@pimunn.ru
Жданович Ирина Владимировна (Zhdanovich Irina Vladimirovna), доцент, кандидат химических наук, доцент кафедры общей химии Russian Federation

M. S. Piskunovа

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Email: rector@pimunn.ru
Пискунова Марина Сергеевна (Piskunovа Marina Sergeevna), доцент, кандидат химических наук., доцент кафедры общей химии Russian Federation

A. N. Lineva

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Email: rector@pimunn.ru
Линева Альбина Николаевна (Lineva Al’bina Nikolaevna), доцент, кандидат химических наук, доцент кафедры общей химии Russian Federation

A. N. Novikova

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Email: rector@pimunn.ru
Новикова Антонина Николаевна (Novikova Antonina Nikolaevna), кандидат химических наук, старший преподаватель кафедры общая химия Russian Federation

P. A. Loginov

Privolzhsky Research Medical University of the Ministry of Health of the Russian Federation, 603950, Nizhny Novgorod

Email: rector@pimunn.ru
Логинов Петр Александрович (Loginov Petr Alexandrovich), младший научный сотрудник центра доклинических исследований ЦНИЛ Russian Federation

References

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Copyright (c) 2019 Kadomtsevа A.V., Zhdanovich I.V., Piskunovа M.S., Lineva A.N., Novikova A.N., Loginov P.A.


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