Synthesis of Heterocycles Based on 4,5-Dichlorophthalonitrile

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Resumo

The SNAr reaction of 4,5-dichlorophthalonitrile with various bifunctional nucleophiles was carried out in anhydrous DMF in the presence of K2CO3 as a deprotonating agent. It was shown that 4,5-dichlorophthalonitrile can be successfully employed in the synthesis of heterocyclic compounds; however, in some cases, these reactions may either give product mixtures or result in an unexpected rearrangement.

Sobre autores

V. Baklagin

Yaroslavl State Technical University

Email: baklaginvl@ystu.ru
ORCID ID: 0009-0003-5361-9085
Yaroslavl, Russia

V. Bukhalin

Yaroslavl State Technical University

ORCID ID: 0009-0008-9150-2802
Yaroslavl, Russia

I. Abramov

Yaroslavl State Technical University

ORCID ID: 0000-0002-8204-1660
Yaroslavl, Russia

V. Aleksandriiskii

Ivanovo State University of Chemistry and Technology

ORCID ID: 0000-0002-7986-6573
Ivanovo, Russia

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