Развитие представлений о клеточном электрогенезе и возбудимости и электрофизиологическая школа П.Г. Костюка

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Аннотация

Становление и развитие клеточной физиологии в СССР в значительной степени ассоциируется с именем академика Платона Григорьевича Костюка, выдающегося ученого с мировым именем. Его активная научная деятельность пришлась на вторую половину ХХ в. – период бурного развития электрофизиологии, сопровождавшегося значимыми достижениями, отмеченными тремя Нобелевскими премиями. В то время электрофизиология была фактически единственной областью биологии, в которой были разработаны методы и подходы для анализа физиологических процессов в тканях и клетках в режиме реального времени. Цель данного эссе – осветить ретроспективные аспекты становления электрофизиологии и очертить вклад школы П.Г. Костюка в этот процесс.

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С. С. Колесников

Федеральное государственное бюджетное учреждение науки Институт биофизики клетки РАН, ФИЦ ПНЦБИ РАН

Автор, ответственный за переписку.
Email: staskolesnikov@yahoo.com
Россия, Пущино, Московская обл., 142290

Список литературы

  1. Брежестовский П. Миссионер в науке // Троицкий вариант. 2010. № 54. C. 8.
  2. Бертолон П. Об электрической материи тела человеческого, в здоровом и болезненном состоянии. Унив. тип., у В. Окорокова. М. 1789. 454 с.
  3. Веселовский Н.С., Костюк П.Г., Цындренко А.Я. “Медленные” натриевые каналы в соматической мембране нейронов спинальных ганглиев новорожденных крыс // Доклады АН СССР. 1980. Т. 250. № 1. С. 216–218.
  4. Костюк П.Г. Микроэлектродная техника. Издательство АН УССР. Киев. 1960. 131 с.
  5. Костюк П.Г. Двухнейронная рефлекторная дуга. Медгиз. М. 1959. 256 с.
  6. Костюк П.Г. Над океаном времени. Наукова думка. Киев. 2005. 199 с.
  7. Крышталь O.A., Пидопличко В.П. Внутриклеточная перфузия гигантских нейронов улитки // Нейрофизиология. 1975. Т. 7. С. 327–329.
  8. Ajita R. Galen and his contribution to anatomy: A Review // J. Evol. Med. Dent. Sci. 2015. V.4. № 26. P. 4509–4516. https://doi.org/10.14260/jemds/2015/651
  9. Alexander S.P.H., Mathie A., Peters J.A. et al. The concise guide to pharmacology 2021/22: Ion channels // Br. J. Pharm. 2021. V. 178. P. S157–S245. https://doi.org/10.1111/bph.15539
  10. Araki T., Ito M., Kostyuk P.G., Oscarsson O., Oshima T. Injection of alkaline cations into cat spinal motoneurones // Nature 1962. V. 196. P. 1319–1320. https://doi.org/10.1038/1961319a0
  11. Armstrong C.M., Binstock L. Anomalous rectification in the squid giant axon injected with tetraethylammonium chloride // J. Gen. Physiol. 1965. V. 48. № 5. P. 859–872. https://doi.org/10.1085/jgp.48.5.859
  12. Armstrong C. Interference of injected tetra-n-propyl-ammonium bromide with outward sodium ion current in squid giant axons // Nature. 1966. V. 211. № 5945. P. 322–323. https://doi.org/10.1038/211322a0
  13. Armstrong C.M. Ionic pores, gates, and gating currents // Q. Rev. Biophys. 1974. V. 7. № 2. P. 179–210. https://doi.org/10.1017/s0033583500001402
  14. Armstrong C.M., Hollingworth S. Na+ and K+ channels: history and structure // Biophysical J. 2021. V. 120. № 5. P. 756–763. https://doi.org/10.1016/j.bpj.2021.01.013
  15. Bean R.C., Shepherd W.C., Chan H. et al. Discrete conductance fluctuations in lipid bilayer protein membranes // J. Gen. Physiol. 1969. V. 53. № 6. P. 741–757. https://doi.org/10.1085/jgp.53.6.741
  16. Beeler G.W., Jr., Reuter H. Membrane calcium current in ventricular myocardial fibres // J. Physiol. 1970. V. 207. № 1. P. 191–209. https://doi.org/10.1113/jphysiol.1970.sp009056
  17. Belan P., Kostyuk P., Snitsarev V., Tepikin A. Calcium clamp in isolated neurons of the snail Helix pomatia // J. Physiol. 1993. V. 462. P. 47–58. https://doi.org/10.1113/jphysiol.1993.sp019542
  18. Benham C.D., Tsien R.W. A novel receptor-operated Ca-permeable channel activated by ATP in smooth muscle // Nature 1987. V. 328. № 6127. P. 275–278. https://doi.org/10.1038/328275a0
  19. Bezanilla F. Ion channels: From conductance to structure // Neuron 2008. V. 60. № 3. P. 456–468. https://doi.org/10.1016/j.neuron.2008.10.035
  20. Burnstock G., Campbell G., Bennett M., Holman M.E. Inhibition of the smooth muscle of the taenia coli // Nature 1963. V. 200. P. 581–582. https://doi.org/10.1038/200581a0
  21. Burnstock G. Purinergic signalling: from discovery to current developments // Exp. Physiol. 2014. V. 99. № 1. P. 16–34. https://doi.org/10.1113/expphysiol.2013.071951
  22. Carmeliet E. From Bernstein’s rheotome to Neher-Sakmann’s patch electrode. The action potential // Physiol. Rep. 2019. V. 7. № 1. e13861.
  23. Cobb M. Timeline: Exorcizing the animal spirits: Jan Swammerdam on nerve function // Nature Rev. Neurosci. 2002. V. 3. № 5. P. 395–400. https://doi.org/10.1038/nrn806
  24. Cohen I.B. Benjamin Franklin’s experiments. Harvard University Press. Cambridge. 1941. 451 p.
  25. Cole, K.S., Curtis H.J. Electric impedance of the squid giant axon during activity // J. Gen. Physiol. 1939. V. 22. № 5. P. 649–670. https://doi.org/10.1085/jgp.22.5.649
  26. Cole K.S. Dynamic electrical characteristics of the squid axon membrane // Arch. Sci. Physiol. 1949. V. 3. P. 253–258.
  27. Conti F., Wanke E. Channel noise in nerve membranes and lipid bilayers // Q. Rev. Biophys. 1975. V. 8. № 4. P. 451–506. https://doi.org/10.1017/s0033583500001967
  28. Curtis H.J., Cole K.S. Membrane action potentials from the squid giant axon // J. Cell. Comp. Physiol. 1940. V. 15. № 2. P. 147–157. https://doi.org/10.1002/JCP.1030150204
  29. Danielli J.F., Davson H. A contribution to the theory of permeability of thin films // J. Cell. Comp. Physiol. 1935. V. 5. № 4. P. 495–508. https://doi.org/10.1002/jcp.1030050409
  30. Eccles J.C., Kostyuk P.G., Schmidt R.F. Central pathways responsible for depolarization of primary afferent fibres // J. Physiol. 1962. V. 161. № 2. P. 237–257. https://doi.org/10.1113/jphysiol.1962.sp006884
  31. Eccles J.C., Kostyuk P.G., Schmidt R.F. Presynaptic inhibition of the central actions of flexor reflex afferents // J. Physiol. 1962. V. 161. P. 258–281. https://doi.org/10.1113/jphysiol.1962.sp006885
  32. Fatt P, Katz B. The electrical properties of crustacean muscle fibres // J. Physiol. 1953. V. 120. № 1–2. P. 171–204. https://doi.org/10.1113/jphysiol.1953.sp004884
  33. Fatt P., Ginsborg B.L. The ionic requirements for the production of action potentials in crustacean muscle fibres // J. Physiol. 1958. V. 142. № 3. P. 516–543. https://doi.org/10.1113/jphysiol.1958.sp006034
  34. Fedulova S.A., Kostyuk P.G., Veselovsky N.S. Calcium channels in the somatic membrane of the rat dorsal root ganglion neurons, effect of cAMP // Brain Res. 1981. V. 214. № 1. P. 210–214. https://doi.org/10.1016/0006-8993(81)90457-1
  35. Finkelstein G. Mechanical neuroscience: Emil du Bois-Reymond’s innovations in theory and practice // Front. Syst. Neurosci. 2015. V. 9. P. 133. https://doi.org/10.3389/fnsys.2015.00133
  36. Galvani L. De viribus electricitatis in motu musculari. Commentarius. (Commentary on the effects of electricity on muscular motion). De Bononiesi Scientarium et Ertium Instituto atque // Academia Commentarii. 1791. V. 7. P. 363–418.
  37. Geduldig D., Junge D. Sodium and calcium components of action potential in the Aplisia giant neurone // J. Physiol. 1968. V. 199. № 2. P. 347–365. https://doi.org/10.1113/jphysiol.1968.sp008657
  38. Geduldig D., Gruener R. Voltage clamp of the Aplysia giant neurone: early sodium and calcium currents // J. Physiol. 1970. V. 211. № 1. P. 217–244. https://doi.org/10.1113/jphysiol.1970.sp009276
  39. Gerasimov V.D., Kostyuk, P.G., Maiskii V.A. The influence of divalent cations on the electrical characteristics of membranes of giant neurons // Biofizika 1965. V. 10. P. 447–453.
  40. González C., Baez-Nieto D., Valencia I., Oyarzún I. et al. K+ channels: function-structural overview // Compr. Physiol. 2012. V. 2. № 3. P. 2087–2149. https://doi.org/10.1002/cphy.c110047
  41. Gorter E., Grendel F. On bimolecular layers of lipids on the chromocytes of the blood // J. Exp. Med. 1925. V. 41. № 4. P. 439–443. https://doi.org/10.1084/jem.41.4.439
  42. Hagiwara S., Nakajima S. Differences in Na and Ca spikes as examined by application of tetrodotoxin, procaine, and manganese ions // J. Gen. Physiol. 1966. V. 49. № 4. P. 793–806. https://doi.org/10.1085/jgp.49.4.793
  43. Hales S. Statical essays: containing haemastaticks. V. 2. W. Innys et al. London. 1733.
  44. Hamill O., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches // Pflügers Arch. 1981. V. 391. № 2. P. 85–100. https://doi.org/10.1007/BF00656997
  45. Hunter J. Anatomical Observations on the Torpedo // Philosoph. Transac. 1773. V. 63. P. 481–489. https://doi.org/10.1098/rstl.1773.0040
  46. Hille B. The selective inhibition of delayed potassium currents in nerve by tetraethylammonium ion // J. Gen. Physiol. 1967. V. 50. № 5. P. 1287–1302. https://doi.org/10.1085/jgp.50.5.1287
  47. Hille B. Pharmacological modifications of the sodium channels of frog nerve // J. Gen. Physiol. 1968. V. 51. № 2. P. 199–219. https://doi.org/10.1085/jgp.51.2.199
  48. Hille B. Ionic channels in nerve membranes // Prog. Biophys. Mol. Biol. 1970. V. 21. P. 1–32. https://doi.org/10.1016/0079-6107(70)90022-2
  49. Hille B. The permeability of the sodium channel to organic cations in myelinated nerve // J. Gen. Physiol. 1971. V. 58. № 6. P. 599–619. https://doi.org/10.1085/jgp.58.6.599
  50. Hille B. The permeability of the sodium channel to metal cations in myelinated nerve // J. Gen. Physiol. 1972. V. 59. № 6. P. 637–658. https://doi.org/10.1085/jgp.59.6.637
  51. Hille B. Ion channels of excitable membranes (3rd ed). Sinauer. Sunderland (Mass). 2001. 814 p.
  52. Hladky S.B., Haydon D.A. Discreteness of conductance change in bimolecular lipid membranes in the presence of certain antibiotics // Nature 1970. V. 225. № 5231. P. 451–453. https://doi.org/10.1038/225451a0
  53. Hodgkin A.L., Huxley A.F. Action potentials recorded from inside a nerve fibre // Nature 1939. V. 144. P. 710–711. https://doi.org/10.1038/144710A0
  54. Hodgkin A.L., Huxley A.F., Katz B. Ionic currents underlying activity in the giant axon of the squid // Arch. Sci. Physiol. 1949. V. 3. P. 129–150.
  55. Hodgkin A.L., Katz B. The effect of sodium ions on the electrical activity of the giant axon of the squid // J. Physiol. 1949. V. 108. № 1. P. 37–77. https://doi.org/10.1113/jphysiol.1949.sp004310
  56. Hodgkin A.L. The ionic basis of electrical activity in nerve and muscle // Biol. Rev. 1951. V. 26. № 4. P. 339–409. https://doi.org/10.1111/j.1469-185X.1951.tb01204.x
  57. Hodgkin A.L., Huxley A.F. Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo // J. Physiol. 1952. V. 116. № 4. P. 449–472. https://doi.org/10.1113/jphysiol.1952.sp004717
  58. Hodgkin A.L., Huxley A.F. The components of membrane conductance in the giant axon of Loligo // J. Physiol. 1952. V. 116. № 4. P. 473–496. https://doi.org/10.1113/jphysiol.1952.sp004718
  59. Hodgkin A.L., Huxley A.F. The dual effect of membrane potential on sodium conductance in the giant axon of Loligo // J. Physiol. 1952. V. 116. № 4. P. 497–506. https://doi.org/10.1113/jphysiol.1952.sp004719
  60. Hodgkin A.L., Huxley A.F. Movement of sodium and potassium ions during nervous activity // Cold Spring Harb Symp Quant Biol 1952. V. 17. P. 43–52. https://doi.org/10.1101/SQB.1952.017.01.007
  61. Hodgkin A.L., Huxley A.F. A quantitative description of membrane current and its application to conduction and excitation in nerve // J. Physiol. 1952. V. 117. № 4. P. 500–544. https://doi.org/10.1113/jphysiol.1952.sp004764
  62. Hodgkin A.L., Huxley A.F. Propagation of electrical signals along giant nerve fibers // Proc. R. Soc. Lond. B Biol. Sci. 1952. V. 140. № 899. P. 177–183. https://doi.org/10.1098/rspb.1952.0054
  63. Islam M.S. Calcium signaling: From basic to bedside // Adv. Exp. Med. Biol. 2020. V. 1131. P. 1–6. https://doi.org/10.1007/978-3-030-12457-1_1
  64. Katz B. Mechanisms of synaptic transmission // Rev. Mod. Phys. 1959. V. 31. № 2. P. 524–531. https://doi.org/10.1103/RevModPhys.31.524
  65. Katz B., Miledi R. Ionic requirements of synaptic transmitter release // Nature 1967. V. 215. № 5101. P. 651. https://doi.org/10.1038/215651a0
  66. Katz B., Miledi R. The role of calcium in neuromuscular facilitation // J. Physiol. 1968. V. 195. № 2. P. 481–492. https://doi.org/10.1113/jphysiol.1968.sp008469
  67. Kostyuk P.G., Krishtal O.A., Doroshenko P.A. Calcium currents in snail neurones. I. Identification of calcium current // Pflugers Arch. 1974. V. 348. № 2. P. 83–93. https://doi.org/10.1007/BF00586471
  68. Kostyuk P.G., Krishtal O.A., Doroshenko P.A. Calcium currents in snail neurones. II. The effect of external calcium concentration on the calcium inward current // Pflugers Arch. 1974. V. 348. № 2. P. 95–104. https://doi.org/10.1007/BF00586472
  69. Kostyuk P.G., Krishtal O.A., Pidoplichko V.I. Effects of internal fluoride and phosphate on membrane currents during intracellular dialysis of nerve cells // Nature 1975. V. 257. № 5528. P. 691–693. https://doi.org/10.1038/257691a0
  70. Kostyuk P.G., Krishtal O.A., Pidoplichko V.I. Asymmetrical displacement currents in nerve cell membrane and effect of internal fluoride // Nature 1977. V. 267. № 5606. P. 70–72. https://doi.org/10.1038/267070a0
  71. Kostyuk P.G., Krishtal O.A., Shakhovalov Y.A. Separation of sodium and calcium currents in the somatic membrane of mollusc neurons // J. Physiol. 1977. V. 270. № 3. P. 545–568 https://doi.org/10.1113/jphysiol.1977.sp011968
  72. Kostyuk P.G., Veselovsky N.S., Fedulova S.A. Ionic currents in the somaticmembrane of rat dorsal root ganglion neurons-II. Calcium currents // Neurosci. 1981. V. 6. № 5. 2431–2437. https://doi.org/10.1016/0306-4522(81)90090-7
  73. Kostyuk P.G., Krishtal O.A., Pidoplichko V.I. Intracellular perfusion // J. Neurosci. Methods 1981. V. 4. № 3. P. 201–210. https://doi.org/10.1016/0165-0270(81)90032-7
  74. Kostyuk P.G., Veselovsky N.S., Tsyndrenko A.Y. Ionic currents in the somatic membrane of rat dorsal root ganglion neurons-I. Sodium currents // Neurosci. 1981. V. 6. № 2. P. 2423–2430. https://doi.org/10.1016/0306-4522(81)90088-9
  75. Kostyuk P.G. Metabolic control of ionic channels in the neuronal membrane // Neurosci. 1984. V. 3. № 4. P. 983–989. https://doi.org/10.1016/0306-4522(84)90282-3
  76. Kostyuk P.G. Intracellular perfusion of nerve cells and its effects on membrane currents // Physiol. Rev. 1984. V. 64. № 2. P. 435–454. https://doi.org/10.1152/physrev.1984.64.2.435
  77. Kostyuk P.G., Belan P.V., Tepikin A.V. Free calcium transients and oscillations in nerve cells // Exp. Brain Res. 1991. V. 83. № 2. P. 459–464. https://doi.org/10.1007/BF00231173
  78. Kostyuk P.G., Kirischuk S.I. Spatial heterogeneity of caffeine- and inositol 1,4,5-trisphosphate-induced Ca2+ transients in isolated snail neurons // Neurosci. 1993. V. 53. № 4. P. 943–947. https://doi.org/10.1016/0306-4522(93)90479-y
  79. Kostyuk P., Verkhratsky A. Calcium signalling in the nervous system. Wiley &Sons. Chichester, 1995. 220 p.
  80. Krishtal O.A., Magura I.S. Calcium ions as inward current carriers in mollusk neurons // Comp. Biochem. Physiol. 1970. V. 85. № 4. P. 857–866. https://doi.org/10.1016/0010-406x(70)90080-0
  81. Krishtal O.A., Pidoplichko V.I. A receptor for protons in the nerve cell membrane // Neurosci. 1980. V. 5. № 12. P. 2325–2327. https://doi.org/10.1016/0306-4522(80)90149-9
  82. Krishtal O.A., Pidoplichko V.I. A receptor for protons in the membrane of sensory neurons may participate in nociception // Neurosci. 1981. V. 6. № 12. P. 2599–2601. https://doi.org/10.1016/0306-4522(81)90105-6
  83. Krishtal O.A., Marchenko S.M., Obukhov A.G. Cationic channels activated by extracellular ATP in rat sensory neurons // Neurosci. 1988. V. 27. № 3. P. 995–1000. https://doi.org/10.1016/0306-4522(88)90203-5
  84. Kruger L.C., Isom L.L. Voltage-Gated Na+ Channels: Not just for conduction. Cold Spring Harb // Perspect. Biol. 2016. V. 8. № 6. a02926. https://doi.org/10.1101/cshperspect.a029264
  85. Ling G.N., Gerard R.W. The normal membrane potential of frog sartorius fibers // J. Cell. Comp. Physiol. 1949. V. 34. № 3. P. 383–396. https://doi.org/10.1002/jcp.1030340304
  86. Magura I.S. Action potentials of the mollusc giant neurons in solutions with a change in sodium and calcium concentrations // Neurophysiol. 1969. V. 1. P. 109–117. https://doi.org/10.1113/jphysiol.1968.sp008657
  87. Marmont G. Studies on the axon membrane; a new method // J. Cell. Comp. Physiol. 1949. V. 34. № 3. P. 351–382. https://doi.org/10.1002/jcp.1030340303
  88. Miller C. Ion Channel Reconstitution. Springer New York, New York, 1984. 577 p. https://doi.org/10.1007/978-1-4757-1361-9
  89. Mueller P., Rudin D.O., Tien H.T., Wescott W.C. Reconstitution of cell membrane structure in vitro and its transformation into an excitable system // Nature. 1962. V. 194. P. 979–980. https://doi.org/10.1038/194979a0
  90. Mueller P., Rudin D.O. Induced excitability in reconstituted cell membrane structure // J. Theor. Biol. 1963. V. 4. № 3. P. 268–280. https://doi.org/10.1016/0022-5193(63)90006-7
  91. Nakajo K., Kasuya G. Modulation of potassium channels by transmembrane auxiliary subunits via voltage-sensing domains // Physiol. Rep. 2024. V. 12. № 6. e15980. https://doi.org/10.14814/phy2.15980
  92. Narahashi T.J., Moore J.W., Scott W.R. Tetrodotoxin blockage of sodium conductance increase in lobster giant axon // J. Gen. Physiol. 1964. V. 47. № 5. P. 965–974. https://doi.org/10.1085/jgp.47.5.965
  93. Neher E., Lux H.D. Voltage clamp on Helix pomatia neuronal membrane; current measurement over a limited area of the soma surface // Pflugers Arch. 1969. V. 311. № 3. P. 272-277. https://doi.org/10.1007/BF00590532
  94. Neher E., Sakmann B. Single-channel currents recorded from membrane of denervated frog muscle fibres // Nature. 1976. V. 260. № 5554. P. 799–802. https://doi.org/10.1038/260799a0
  95. Neher E., Sakmann B., Steinbach J.H. The extracellular patch clamp: a method for resolving currents through individual open channels in biological membranes // Pflugers Arch. 1978. V. 375. № 2. P. 219–228. https://doi.org/10.1007/BF00584247
  96. Newton I. Principia Mathematica. Sir Isaac Newton’s Mathematical Principles of Natural Philosophy and his System of the World: translated into English by Andrew Motte in 1729. University of California Press. Berkeley. 1934. 680 p.
  97. Nilius B. Pflügers Archiv and the advent of modern electrophysiology. From the first action potential to patch clamp // Pflugers Arch. 2003. V. 447. P. 267–271. https://doi.org/10.1007/s00424-003-1156-2
  98. Pattison L.A., Callejo G., St. John. Smith. E. Evolution of acid nociception: ion channels and receptors for detecting acid // Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2019. V. 374. № 1785. 20190291. https://doi.org/10.1098/rstb.2019.0291
  99. Piccolino M. Animal electricity and the birth of electrophysiology: the legacy of Luigi Galvani // Brain Res. Bull. 1998. V. 46. № 5. P. 381–407. https://doi.org/10.1016/s0361-9230(98)00026-4
  100. Piccolino M. A “Lost time” between science and literature: the “Temps Perdu” from Hermann von Helmholtz to Marcel Proust // Audiologic. Med. 2009. V. 1. № 4. P. 261–270. https://doi.org/10.1080/16513860310023218
  101. Purves R.D. Ed. Microelectrode methods for intracellular recording and ionophoresis. Academic Press, London. 1981. 146 p. https://doi.org/10.1113/expphysiol.1982.sp002669
  102. Reuter H. The dependence of slow inward current in Purkinje fibres on the extracellular calcium-concentration // J. Physiol. 1967. V. 192. № 2. P. 479–492. https://doi.org/10.1113/jphysiol.1967.sp008310
  103. Rojas E., Armstrong C. Sodium conductance activation without inactivation in pronase-perfused axons // Nature: New Biology. 1971. V. 229. № 6. P. 177–178. https://doi.org/10.1038/newbio229177a0
  104. Rougier O., Vassort G., Garnier D., Gargouil Y.M., Coraboeuf E. Existence and role of a slow inward current during the frog atrial action potential // Pflugers Arch. 1969. V. 308. № 2. P. 91–110. https://doi.org/10.1007/BF00587018
  105. Sakmann B., Neher E. Eds. Single channel recording. Second edition. Plenum Press, New York, 1995. 700 p. https://doi.org/10.1007/978-1-4419-1229-9
  106. Sanchez-Sandoval A.L., Hernández-Plata E., Gomora J.C. Voltage-gated sodium channels: from roles and mechanisms in the metastatic cell behavior to clinical potential as therapeutic targets // Front. Pharmacol. 2023. V. 14. 1206136. https://doi.org/10.3389/fphar.2023.1206136
  107. Storozhuk M., Cherninskyi A., Maximyuk O. Isaev D., Krishtal O. Acid-sensing ion channels: Focus on physiological and some pathological roles in the brain // Curr. Neuropharmacol. 2021. V. 19. № 9. P. 1570–1589. https://doi.org/10.2174/1570159X19666210125151824
  108. Tasaki I., Hagiwar A.S. Demonstration of two stable potential states in the squid giant axon under tetraethylammonium chloride // J. Gen. Physiol. 1957. V. 40. № 6. P. 859–885. https://doi.org/10.1085/jgp.40.6.859
  109. Verkhratsky A., North A.R., Petersen O.H., Krishtal O. In memoriam: Platon Kostyuk (1924–2010) // Cell Calcium. 2010. V. 44. № 1. P. 91–93. https://doi.org/10.1016/j.ceca.2010.07.003
  110. Volta A. On the electricity excited by the mere contact of conducting substances of different kinds // Philosophical Transactions of the Royal Society of London. 1800. P. 403–431. https://doi.org/10.1098/rstl.1800.0018
  111. Waldmann R., Champigny G., Bassilana F. Heurteaux, C., Lazdunski, M. A proton-gated cation channel involved in acid-sensing // Nature. 1997. V. 386. № 6621. P. 173–177. https://doi.org/10.1038/386173a0
  112. Walsh J. Of the Electric Property of the Torpedo // Philosophical Transactions. 1773. V. 63. P. 461–480. https://doi.org/10.1098/rstl.1773.0039
  113. Young J.Z. Structure of nerve fibres and synapses in some invertebrates // Cold Spring Harbor Symp. Quant. Biol. 1936. V. 4. № 5. P. 1–6. https://doi.org/10.1101/SQB.1936.004.01.001
  114. Xu L., Ding X., Wang T. Mou S., Sun H., Hou T. Voltage-gated sodium channels: structures, functions, and molecular modeling // Drug Discovery Today. 2019. V. 24. № 7. P. 1389–1397. https://doi.org/10.1016/j.drudis.2019.05.014
  115. Zhu Y., Hu X., Wang L. Zhang J., Pan X., Li Y. et al. Recent advances in acid-sensitive ion channels in central nervous system diseases // Curr. Pharm. Des. 2022. V. 28. № 17. P. 1406–1411. https://doi.org/10.2174/1381612828666220422084159

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2. Рис. 1. Платон Григорьевич Костюк (1924–2010.).

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3. Рис. 2. Эксперименты Гальвани.

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4. Рис. 3. Астатический гальванометр Нобили.

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5. Рис. 4. Электромеханический реатом Бернштейна.

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6. Рис. 5. Потенциал действия (negative variation) в дискретной реконструкции Бернштейна [22].

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7. Рис. 6. Эквивалентная электрическая схема гигантского аксона кальмара [61].

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8. Рис. 7. Основные моды метода patch clamp.

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9. Рис 8. Внутриклеточная перфузия.

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