Synthesis of 1,3-Dimethylpyrimido[4′,5′:4,5]pyrrolo[1,2-b]-pyridazine-2,4(1H,3H)-diones and their 8,9-dihydro derivatives

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Abstract

Simple and effective methods were proposed for the synthesis of previously undescribed substituted pyrimido[4′,5′:4,5]pyrrolo[1,2-b]pyridazine-2,4(1H,3H)-diones and their 8,9-dihydro derivatives. Structure of the prepared compounds was studied using IR, NMR, UV spectroscopy, quantum chemical calculations and single crystal X-ray diffraction analysis.

About the authors

Yu. N. Tkachenko

Rostov State Medical University

Email: natvi2004@mail.ru
Rostov-on-Don, 344022 Russia

N. I. Vikrishchuk

Southern Federal University

Email: natvi2004@mail.ru
Rostov-on-Don, 344090 Russia

S. I. Levchenkov

Southern Federal University; Federal Research Center "Southern Scientific Center of the Russian Academy of Sciences"

Email: natvi2004@mail.ru
Rostov-on-Don, 344090 Russia; Rostov-on-Don, 344006 Russia

I. A. Estrin

Rostov State Transport University

Email: natvi2004@mail.ru
Rostov-on-Don, 344038 Russia

L. D. Popov

Southern Federal University

Author for correspondence.
Email: natvi2004@mail.ru
Rostov-on-Don, 344090 Russia

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