Assessment of carcinogenic risk from exposure to chlororganic compounds of water of systems of centralized water supply

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Introduction. The problem of providing the population with drinking water with guaranteed quality, safety, and physiological usefulness is highly relevant for many regions of Russia. The use of chlorination for disinfection of the water is a potential cause of the formation of excess concentrations of organochlorine compounds in it, including trihalogenomethanes, which leads to elevated levels of carcinogenic risk. 

The study’s object was: data on the content in water of centralized water supply systems of carcinogenic organochlorine compounds - chloroform, dichlorobromomethane and chlorodibromomethane.

Material and methods. information on the incidence of the population of malignant neoplasms; the results of an experiment to evaluate the effectiveness of the preliminary ammonization method. The paper used methods of health risk assessment, variation statistics, and mathematical modeling. 

Results. The use of preliminary ammonization in Taganrog prevents the formation of trihalogenomethanes and ensures the maintenance of an individual multi-route carcinogenic risk at an acceptable level (9.933 · 10–6). Systematic unreasonable hyper chlorination of river water without prior ammoniation is the main reason for the excess content of chlororganic compounds and the high level of individual carcinogenic risk in the Primorsky rural settlement of the Neklinovsky District - up to 3.234 · 10–3 in 2015. Modeling on the basis of experimental chlorination of natural water indicates the high efficiency of preliminary ammonization in the disinfection mode, which ensures the content of free total active chlorine in tap water in the range from 0.8 to 1.2 mg/l. 

Conclusion. The high efficiency of the application of preliminary ammonization of natural water to prevent the formation of trihalogenomethanes and reduce carcinogenic risk has been confirmed. The priority factor for the formation of excess amounts of organochlorine compounds in drinking water is its hyper chlorination. Promising measures to reduce the carcinogenic risk of trihalogenomethanes in tap water include the systematic monitoring of their content, the use of preliminary ammonization, the exact dosage of chlorine, the deep purification of the source water before chlorination, the replacement of primary chlorination with ultraviolet disinfection, and others.

Sobre autores

Boris Marchenko

Southern Federal University; The branch of the Center of Hygiene and Epidemiology in the Rostov region

Autor responsável pela correspondência
Email: borismarch@gmail.com
ORCID ID: 0000-0001-6173-329X

MD, Ph.D., DSci, professor of the department of the technosphere safety and chemistry of the Institute of Nanotechnologies,
Electronics and Equipment Engineering of the Southern Federal University Russia, Taganrog, 347928, Russian Federation.

e-mail: borismarch@gmail.com

Rússia

Petr Zhuravlev

Rostov Research Institute of Microbiology and Parasitology

Email: noemail@neicon.ru
ORCID ID: 0000-0002-8196-3882
Rússia

Nina Plugotarenko

Southern Federal University

Email: noemail@neicon.ru
ORCID ID: 0000-0003-0853-8510
Rússia

Aleksandra Yuhno

Southern Federal University

Email: noemail@neicon.ru
ORCID ID: 0000-0002-9871-9261
Rússia

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Declaração de direitos autorais © Marchenko B.I., Zhuravlev P.V., Plugotarenko N.K., Yuhno A.I., 2024


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