Synthesis of 4-(N4-methyl-5-aryl-1,2,4-triazole-5-ilmethylthio) cresoxyacetic acids and their sulfonic analogues of new potential PPARδ/β agonists

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Abstract

A nine-stage scheme for the synthesis of 4-( N 4-methyl-5-aryl-1,2,4-triazole-5-ilmethylthio) cresoxyacetic acids of new potential PPARδ/β agonists based on substituted benzoic acids has been developed. Their sulfon-containing analogues were obtained from the intermediate esters of such acids.

About the authors

D. V Minin

Mendeleev University of Chemical Technology

Email: minin30@mail.ru

S. V Popkov

Mendeleev University of Chemical Technology

Email: minin30@mail.ru

G. V Tsaplin

Mendeleev University of Chemical Technology

Email: minin30@mail.ru

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